Depression fatigue appears at the cellular level in brain and blood
Scientists have identified an unusual energy signature in young adults with depression: cells in both the brain and blood appear highly active at rest but lose ground when demand rises.
The finding recasts fatigue as a measurable feature of the illness, one that may surface before treatment choices become clearer.
One of the biggest challenges with mental health is that almost all diagnoses rely on abstract rather than concrete assessments. It's usually done by self-reporting or observation, which is neither precise nor objective, unlike most illnesses that have scientific tests. So finding any kind of biomarker is extremely useful.
Scientists have identified an unusual energy signature in young adults with depression: cells in both the brain and blood appear highly active at rest but lose ground when demand rises.
The finding recasts fatigue as a measurable feature of the illness, one that may surface before treatment choices become clearer.
One of the biggest challenges with mental health is that almost all diagnoses rely on abstract rather than concrete assessments. It's usually done by self-reporting or observation, which is neither precise nor objective, unlike most illnesses that have scientific tests. So finding any kind of biomarker is extremely useful.
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Date: 2026-03-23 01:55 am (UTC)