>> Yeah, they'll want Alicia or some other healer to look *all* the centaurs over. Best if it's someone who can do anatomical drawing to detail the variations in how the splicing was done and any other changes.<<
She has been out to visit them. Not all of them were interested. Miriam being willing to model is great and will help, but there's no guarantee any given centaur is "like" any other, beyond what's readily visible. They are similar because they're part of the same cohort, but with some dramatic variations (wings, zebra) you just can't count on that similarity.
>>Some of the things that could *big* issues.<<
All of them have something significant wrong already known.
>> Unless the equine parts where grown specially with human DNA, there are gonna be immune system weirdnesses. Every thing from blood types on.<<
These weren't grown. He stapled half-humans to half-horses. Hence needing victims with certain superpowers to survive the process, although he certainly helped it along with his mad science.
>> *Something* had to be done to avoid autoimmune disorders. Otherwise they'd be horribly ill or dead.
Immunosuppressants are unlikely as that'd have gotten them sick from a lot of things after they got out.<<
There's a way you can turn the immune system off and back on again so it reboots, and whatever is in the system at the time gets read as 'self.' It's very useful, but hard to find.
>> This is going to make blood transfusions "interesting".<<
Probably impossible, unless 1) some of the centaurs are a match for each other, or 2) a synthetic can be produced. Neither pure human nor pure horse would likely be close enough.
>>Also means that there may be problems with oddball allergic reaction.<<
Probably so.
>>And the combined digestive system is gonna be really weird too. The human part can't handle rough stuff like grass and hay. The equine part would need major mods to deal with meat and many other things.<<
At least one of them needs a special diet. In general, the human stomach can usually digest meat (though not necessarily all of them can do it) but the horse parts can't. That means eat small amounts so it gets digested before passed along. The horse parts require more fuel and more bulk, but it doesn't have to be dried. Humans can eat some types of grass, just can't digest most of it; the horse part does that fine. So it's a challenge, but not impossible.
>>They'll have to have had some significant work done on the nose and throat to allow for the extra airflow required. Ditto for the larger volume of food required.<<
Yep.
>> The limited immunity for black hats turning in another black hat reminds me of something seen in old Westerns: "Just be outta town by sunset..." and similar comments.<<
Thoughts
She has been out to visit them. Not all of them were interested. Miriam being willing to model is great and will help, but there's no guarantee any given centaur is "like" any other, beyond what's readily visible. They are similar because they're part of the same cohort, but with some dramatic variations (wings, zebra) you just can't count on that similarity.
>>Some of the things that could *big* issues.<<
All of them have something significant wrong already known.
>> Unless the equine parts where grown specially with human DNA, there are gonna be immune system weirdnesses. Every thing from blood types on.<<
These weren't grown. He stapled half-humans to half-horses. Hence needing victims with certain superpowers to survive the process, although he certainly helped it along with his mad science.
>> *Something* had to be done to avoid autoimmune disorders. Otherwise they'd be horribly ill or dead.
Immunosuppressants are unlikely as that'd have gotten them sick from a lot of things after they got out.<<
There's a way you can turn the immune system off and back on again so it reboots, and whatever is in the system at the time gets read as 'self.' It's very useful, but hard to find.
>> This is going to make blood transfusions "interesting".<<
Probably impossible, unless 1) some of the centaurs are a match for each other, or 2) a synthetic can be produced. Neither pure human nor pure horse would likely be close enough.
>>Also means that there may be problems with oddball allergic reaction.<<
Probably so.
>>And the combined digestive system is gonna be really weird too. The human part can't handle rough stuff like grass and hay. The equine part would need major mods to deal with meat and many other things.<<
At least one of them needs a special diet. In general, the human stomach can usually digest meat (though not necessarily all of them can do it) but the horse parts can't. That means eat small amounts so it gets digested before passed along. The horse parts require more fuel and more bulk, but it doesn't have to be dried. Humans can eat some types of grass, just can't digest most of it; the horse part does that fine. So it's a challenge, but not impossible.
>>They'll have to have had some significant work done on the nose and throat to allow for the extra airflow required. Ditto for the larger volume of food required.<<
Yep.
>> The limited immunity for black hats turning in another black hat reminds me of something seen in old Westerns: "Just be outta town by sunset..." and similar comments.<<
Exactly!